02048cam a22003135a 4500 017626671 OSt 20171226105758.0 151116t2016 sz frbf 001 0 eng d 9783319053912 StDuBDS eng StDuBDS EG-ScBUE 615.19 DRU 22 Drug discovery and evaluation : pharmacological assays / edited by Franz J. Hock. 4th ed. Cham : Springer International Publishing, c.2016. 4 v. : ill. ; 24 cm. Springer reference Includes bibliographical references and index. v. 1. -- v. 2. -- v. 3. The 4th edition of this successful reference book contains an updated selection of the most frequently used assays for reliably detecting the pharmacological effects of potential drugs. Effects covered include cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal and immunomodulatory activities. Each of the more than 1,000 assays comprises a detailed protocol outlining the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. In addition, animal models of rare diseases are described. For this 4th edition, all existing chapters have been revised and completely updated. A large number of assays were added. Sections that have been specifically enlarged include - Pharmacological assays in thrombosis and haemostasis, - Antidiabetic activity (includes completely new chapters such as Biochemical Methods in Diabetology), - Anti-atherosclerotic activity. New chapters are added such as Auditory Pharmacology, Oncology Activity, Stem Cells, Omics, Personalized Medicine, etc Pharmacology, Experimental. BUEsh Drugs Design. BUEsh 30136 Drugs Testing. BUEsh BUEsh PPhrm October2017 December2017 Hock, Franz J., editor. Print version : 9783319053912 ddc 25528 25500 0 0 ddc 0 0 Baccah MAIN MAIN 1ST 2017-10-31 Purchase 0 615.1903 DRU 000042353 2025-07-15 00:00:00 REFERENCE v. 4. 0 0 ddc 0 0 Baccah MAIN MAIN 1ST 2017-12-26 Purchase 32500.00 0 615.1903 DRU 000047016 2025-07-15 00:00:00 REFERENCE v. 1. 0 0 ddc 0 0 Baccah MAIN MAIN 1ST 2017-12-26 Purchase 0 615.1903 DRU 000047017 2025-07-15 00:00:00 REFERENCE v. 2. 0 0 ddc 0 0 Baccah MAIN MAIN 1ST 2017-12-26 Purchase 0 615.1903 DRU 000047018 2025-07-15 00:00:00 REFERENCE v. 3.