A practical guide to rational drug design / (Record no. 26919)

MARC details
000 -LEADER
fixed length control field 02208cam a22002895a 4500
001 - CONTROL NUMBER
control field 017472678
003 - CONTROL NUMBER IDENTIFIER
control field Uk
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20181031123521.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 150717s2016 enka frb 001 0 eng d
015 ## - NATIONAL BIBLIOGRAPHY NUMBER
National bibliography number GBB5A6276
Source bnb
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 9780081000984 (hbk.)
040 ## - CATALOGING SOURCE
Original cataloging agency StDuBDS
Language of cataloging eng
Transcribing agency StDuBDS
Modifying agency Uk
-- EG-ScBUE
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 615.19
Item number HON
Edition number 22
100 1# - MAIN ENTRY--PERSONAL NAME
Personal name Hongmao, Sun.
9 (RLIN) 41857
245 12 - TITLE STATEMENT
Title A practical guide to rational drug design /
Statement of responsibility, etc Sun Hongmao.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Cambridge ;
-- Waltham, MA :
Name of publisher, distributor, etc Woodhead Publishing / Elsevier,
Date of publication, distribution, etc c.2016.
300 ## - PHYSICAL DESCRIPTION
Extent 275 p. :
Other physical details ill. (col.) ;
Dimensions 24 cm.
490 0# - Series Statement
Series statement Woodhead Publishing series in biomedicine ;
Volume/sequential designation no. 81
505 0# - FORMATTED CONTENTS NOTE
Title PART I Rational Drug Design 1. Structure of the target is available 2. Structure of the target is unavailable 3. Virtual screening (VS)
-- PART II Chemoinformatics 1. QSAR modeling 2. Processing HTS results 3. Delivering modeling results
520 ## - SUMMARY, ETC.
Summary, etc This book is not going to be an exhaustive survey covering all aspects of rational drug design. Instead, it is going to provide critical know-how through real-world examples. Relevant case studies will be presented and analyzed to illustrate the following: how to optimize a lead compound whether one has high or low levels of structural information; how to derive hits from competitors' active compounds or from natural ligands of the targets; how to springboard from competitors' SAR knowledge in lead optimization; how to design a ligand to interfere with protein-protein interactions by correctly examining the PPI interface; how to circumvent IP blockage using data mining; how to construct and fully utilize a knowledge-based molecular descriptor system; how to build a reliable QSAR model by focusing on data quality and proper selection of molecular descriptors and statistical approaches. A Practical Guide to Rational Drug Design focuses on computational drug design, with only basic coverage of biology and chemistry issues, such as assay design, target validation and synthetic routes.
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Drugs
General subdivision Design.
Source of heading or term BUEsh
9 (RLIN) 30136
651 ## - SUBJECT ADDED ENTRY--GEOGRAPHIC NAME
Source of heading or term BUEsh
653 ## - INDEX TERM--UNCONTROLLED
Resource For college Pharmacy
-- Generalities
Arrived date list October2018
655 ## - INDEX TERM--GENRE/FORM
Form subdivision Reading book
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Print version:
International Standard Book Number 9780081000984
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme Dewey Decimal Classification
Holdings
Withdrawn status Item status Source of classification or shelving scheme Damaged status Not for loan Vendor Home library Current library Shelving location Date acquired Source of acquisition Cost, normal purchase price Total Checkouts Full call number Barcode Date last seen Koha item type
    Dewey Decimal Classification     Baccah Central Library Central Library First floor 31/10/2018 Purchase 2700.00   615.19 HON 000043716 15/07/2025 Book - Borrowing

© BUE Library 2020